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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8745 | PROTAC BRAF-V600E degrader-1 | Compound 23 | Raf |
PROTAC BRAF-V600E degrader-1 (Compound 23) selectively induces degradation of BRAF-V600E but not wildtype BRAF. | |||
Fr12799 | AChE-IN-23 | ||
AChE-IN-23 (compound 3h) is an inhibitor of acetylcholinesterase (AChE) with an IC 50 value of 48.3 μM [1]. | |||
T3222 | 16,17-Epoxypregnenol | 16alpha,17alpha-Epoxypregnenolone | Others |
16,17-Epoxypregnenol is a useful organic compound for research related to life sciences. The catalog number is T3222 and the CAS number is 974-23-2. | |||
T63132 | Amgen-23 | ||
Amgen-23 (compound 23) is a potent inhibitor of sphingosine kinase (SPHK), acting on SPHK1 (IC50: 20 μM) and SPHK2 (IC50: 1.6 μM). amgen-23 can be used in anticancer studies. | |||
T38192 | Unifiram | Others | |
Unifiram is a nootropic agent.1It increases acetylcholine (ACh) release in the rat cerebral cortexin vivoand induces a long-lasting increase in the amplitude of field excitatory postsynaptic potentials (fEPSPs) in the ra... | |||
T74999 | Antibacterial agent 127 | ||
Antibacterial agent 127 (Compound 23) is a potent antibacterial agent [1] . | |||
T83556 | (3β)-3-Hydroxyoleanan-12-one | ||
"(3β)-3-Hydroxyoleanan-12-one (compound 23), a natural product, is isolated from Codonopsis ovata [1]." | |||
T63142 | AChE/HDAC-IN-1 | ||
COX-2-IN-23 (compound A10) is a potent inhibitor of AChE (IC50: 0.12 nM) and HDAC (IC50: 0.23 nM).COX-2-IN-23 exhibits antioxidant and metal chelating properties.COX-2-IN-23 can be used to study Alzheimer's disease. | |||
T79769 | HDAC6-IN-23 | HDAC | |
HDAC6-IN-23 (compound 9), an orally active inhibitor of HDAC6 [1], displays selective enzymatic inhibition. | |||
T62704 | HBV-IN-23 | ||
HBV-IN-23 (Compound 5k) is an inhibitor of HBV DNA replication (IC50: 0.58 μM). HBV-IN-23 inhibits drug-sensitive and drug-resistant strains. HBV-IN-23 induces apoptosis in HepG2 cells and exhibits anti-hepatocellular ca... | |||
T61710 | Antileishmanial agent-7 | ||
Antileishmanial agent-7 (compound 23) exhibits strong antileishmanial activity against Leishmania donovani and L-6, with IC50 values of 6.89 and 259 μM, respectively [1]. | |||
T60841 | SARS-CoV-2-IN-23 | ||
SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1]. | |||
T63184 | CDK5-IN-2 | ||
CDK5-IN-2 (compound 15) is a highly selective CDK5 inhibitor that acts on CDK5/p25 (IC50: 0.2 nM) and CDK2/CycA (IC50: 23 nM). | |||
T72097 | Eleven-Nineteen-Leukemia Protein IN-2 | Epigenetic Reader Domain | |
Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1]. | |||
Fr16627 | 3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine | ||
Compound Fr16627 is a useful organic compound for research related to life sciences. The catalog number is Fr16627 and the CAS number is 20348-23-6. | |||
T79166 | KRAS G12C inhibitor 60 | Ras | |
KRAS G12C Inhibitor 60 (compound 23), a selective inhibitor targeting the Kras-G12C mutation, is utilized in the investigation of lung, colorectal, and pancreatic cancers [1]. | |||
T82098 | ICMT-IN-44 | ||
ICMT-IN-44 (compound 23) serves as an ICMT inhibitor with an IC50 value of 0.167 μM [1]. | |||
T74133 | 23-epi-26-Deoxyactein | ||
23-epi-26-Deoxyactein is a naturally occurring compound exhibiting anti-obesity and anti-cancer properties when administered orally [1] [2] [3]. | |||
T82082 | IDO1-IN-23 | Indoleamine 2,3-Dioxygenase (IDO) | |
IDO1-IN-23 (compound 41) is a potent inhibitor of human indoleamine 2,3-dioxygenase 1 (IDO1), exhibiting an IC50 of 13 μM [1]. | |||
T77931 | PROTAC IRAK3 degrade-1 formic | PROTACs | |
PROTAC IRAK3 Degrade-1 (Compound 23) is a selective and potent IRAK3 degrader, demonstrating an IC50 value of 5 nM [1]. |